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ALYFTREK
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ALYFTREK
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ALYFTREK Lifestyle Interactions
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Vanzacaftor 10mg, Tezacaftor 50mg, Deutivacaftor 125mg, Oral tablet
• Interaction: Grapefruit juice• Severity: Major• Notes for Consumers: Do not take these agents together. Side effects from tezacaftor; ivacaftor may get worse if you take these agents together. These include dark yellow or brown urine, general ill feeling or flu-like symptoms, light-colored stools, loss of appetite, nausea, right upper belly pain, unusually weak or tired, yellowing of the eyes and skin.• Notes for Professionals: Avoid food or drink containing grapefruit juice or Seville oranges during treatment with tezacaftor; ivacaftor. Grapefruit contains one or more components that inhibit CYP3A; both tezacaftor and ivacaftor are CYP3A substrates (ivacaftor is a sensitive substrate).
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.