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CABOTEGRAVIR (CAB oh TEG ra veer) is used for HIV PrEP (pre-exposure prophylaxis), which helps lower the risk of getting HIV through sex. It works by limiting the spread of HIV in the body. It does not prevent other sexually transmitted infections (STIs).
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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This medication is injected into a muscle. It is given by your care team in a hospital or clinic setting. You will receive an injection once every month for the first 2 months, then once every 2 months. Before receiving your first injection, your care team may have you take oral cabotegravir tablets once daily for 1 month to see how well you will tolerate the injection.
Talk to your care team about the use of this medication in children. While it may be prescribed for children as young as 12 years for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Do not take this medication with any of the following:
-Certain medications for seizures, such as carbamazepine, oxcarbazepine, phenobarbital, phenytoin
-Rifampin
-Rifapentine
This medication may also interact with the following:
-Methadone
-Rifabutin
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Visit your care team for regular checks on your progress. Discuss any new symptoms with your care team. You will need to have important blood work done while on this medication.
You will need an HIV test before you receive each injection.
HIV is spread to others through sexual or blood contact. Talk to your care team about how to stop the spread of HIV.
You may experience a local reaction at the injection site; these reactions are common and usually only last a few days. Ask your care team about things you can do to help with these reactions.
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Keep appointments for follow-up doses. It is important not to miss your dose. Call your care team if you are unable to keep an appointment.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
-Thoughts of suicide or self-harm, worsening mood, feelings of depression
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
-Diarrhea
-Fatigue
-Fever
-Headache
-Nausea
-Pain, redness, or irritation at injection site
-Trouble sleeping
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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This medication is given in a hospital or clinic. It will not be stored at home.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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