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LISDEXAMFETAMINE (lis DEX am fet a meen) treats attention-deficit hyperactivity disorder (ADHD). It may also be used to treat binge eating disorders. It works by improving focus and reducing impulsive behavior. It belongs to a group of medications called stimulants.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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Take this medication by mouth. Take it as directed on the prescription label at the same time every day. Use a specially marked oral syringe, spoon, or dropper to measure each dose. Ask your pharmacist if you do not have one. Household spoons are not accurate. You can take this medication with or without food. If it upsets your stomach, take it with food. Keep taking it unless your care team tells you to stop.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your care team about the use of this medication in children. While it may be prescribed for children as young as 6 years for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Do not take this medication with any of the following:
-Ergot alkaloids, such as dihydroergotamine, ergotamine, methylergonovine
-Linezolid
-MAOIs, such as Marplan, Nardil, and Parnate
-Methylene blue
This medication may also interact with the following:
-Acetazolamide
-Alcohol
-Ascorbic acid (vitamin C)
-Opioids
-Sodium bicarbonate
-Some medications for depression, anxiety, or other mental health conditions
-Some medications for migraines, such as sumatriptan
-Some medications used for imaging scans
-Supplements, such as St. John's wort or tryptophan
Other medications may affect the way this medication works. Talk with your care team about all the medications you take. They may suggest changes to your treatment plan to lower the risk of side effects and to make sure your medications work as intended.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.
This medication requires a new prescription from your care team every time it is filled at the pharmacy.
There is a risk of abuse, misuse, and addiction with this medication. It is important to take this medication as directed by your care team.
If you have taken this medication for a long time or take a high dose, your body may rely on it. You may be able to take breaks from this medication during weekends, holidays, or summer vacations. Talk to your care team about what works for you. If your care team wants you to stop this medication permanently, the dose will be slowly lowered over time to reduce the risk of side effects.
Tell your care team if this medication loses its effects, or if you feel you need to take more than the prescribed amount. Do not change your dose without talking to your care team.
Do not take this medication close to bedtime. It may prevent you from sleeping.
Loss of appetite is common when starting this medication. Eating small, frequent meals or snacks can help. Talk to your care team if appetite loss persists. Children should have height and weight checked often while taking this medication.
Tell your care team right away if you notice unexplained wounds on your fingers and toes while taking this medication. You should also tell your care team if you experience numbness or pain, changes in the skin color, or sensitivity to temperature in your fingers or toes.
Contact your care team right away if you have an erection that lasts longer than 4 hours or if it becomes painful. This may be a sign of a serious problem and must be treated right away to prevent permanent damage.
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If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Heart attack—pain or tightness in the chest, shoulders, arms, or jaw, nausea, shortness of breath, cold or clammy skin, feeling faint or lightheaded
-Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing
-Increase in blood pressure
-Irritability, confusion, fast or irregular heartbeat, muscle stiffness, twitching muscles, sweating, high fever, seizure, chills, vomiting, diarrhea, which may be signs of serotonin syndrome
-Mood and behavior changes—anxiety, nervousness, confusion, hallucinations, irritability, hostility, thoughts of suicide or self-harm, worsening mood, feelings of depression
-Prolonged or painful erection
-Raynaud syndrome—cool, numb, or painful fingers or toes that may change color from pale, to blue, to red
-Seizures
-Stroke—sudden numbness or weakness of the face, arm, or leg, trouble speaking, confusion, trouble walking, loss of balance or coordination, dizziness, severe headache, change in vision
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
-Dry mouth
-Headache
-Loss of appetite with weight loss
-Nausea
-Stomach pain
-Trouble sleeping
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep this medication out of reach of children and pets. Store it out of sight in a safe place. Do not share it with others. Misuse of this medication is dangerous and against the law.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Keep the container tightly closed. Get rid of any unused medication 30 days after opening or after it expires, whichever is first.
This medication may cause harm and death if it is taken by other adults, children, or pets. It is important to get rid of the medication as soon as you no longer need it or it is expired. To get rid of this medication:
-Take the medication to a take-back program. Check with your pharmacy or law enforcement to find a location.
-Follow the steps given to you by your pharmacy. You may be given a pre-paid mail-back envelope or disposal product to safely get rid of your medication.
-If other options are not available, check the package insert or medication guide to see if it should be flushed down the toilet or put in your trash at home. If you are not sure, ask your care team. If it is safe to put it in your trash, empty the medication out of the container. Mix it with cat litter, dirt, used coffee grounds, or another unwanted substance. Seal the mixture in a container, such as a plastic bag. Put it in the trash.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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