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BREXAFEMME
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BREXAFEMME Lifestyle Interactions
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Ibrexafungerp 150mg, Oral tablet
• Interaction: Grapefruit juice• Severity: Major• Notes for Consumers: Do not eat grapefruit or drink grapefruit juice while taking Ibrexafungerp without discussing the risks with your health care provider. Side effects from Ibrexafungerp may get worse. Contact your prescriber immediately if you experience any new or worsening side effects, such as diarrhea, nausea, vomiting, abdominal pain, or dizziness.• Notes for Professionals: Advise patients to avoid consuming grapefruit or grapefruit juice while taking ibrexafungerp. Coadministration may result in increased ibrexafungerp exposure and toxicity. Ibrexafungerp is a CYP3A substrate and grapefruit is a strong CYP3A inhibitor. Coadministration with another strong CYP3A inhibitor increased the AUC and Cmax of ibrexafungerp by 5.8-fold and 2.5-fold, respectively.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.