BUSPIRONE (byoo SPYE rone) treats anxiety. It works by balancing the levels of dopamine and serotonin in your brain, substances that help regulate mood.

BUSPIRONE HCL Lifestyle Interactions

  • Buspirone Hydrochloride 10mg, Oral tablet

    • Interaction: Grapefruit juice
    • Severity: Major
    • Notes for Consumers: Do not drink grapefruit juice or eat grapefruit while taking this medication. Grapefruit may alter the effects of your medication. Serious side effects may occur. Contact your care team right away if you experience new or worsening side effects.
    • Notes for Professionals: Advise patients to avoid grapefruit and grapefruit juice during buspirone treatment due to the risk for increased buspirone exposure and adverse reactions. Buspirone is a CYP3A substrate and grapefruit juice is a CYP3A inhibitor.

  • Buspirone Hydrochloride 10mg, Oral tablet

    • Interaction: Food
    • Severity: Major
    • Notes for Consumers: Buspirone may be taken with or without food. However, grapefruit juice and grapefruit-containing foods may increase the risk of side effects of Buspirone, like drowsiness. Do not significantly alter grapefruit juice intake while taking this drug, or avoid grapefruit juice if possible.
    • Notes for Professionals: Buspirone should be taken consistently with or without food because food decreases the presystemic clearance of buspirone.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.