• Image of ERLEADA medication Image of ERLEADA medication
    • ERLEADA

    • QTY 120
    • 60 MG
    • Tablet
    • Near  77381

APALUTAMIDE (A puh LOO tuh mide) treats prostate cancer. It works by blocking the effect of testosterone and other hormones in your body, which may slow or stop cancer cells from spreading or growing.


ERLEADA Lifestyle Interactions

  • Apalutamide 60mg, Oral tablet

    Interaction: Cannabis
    Severity: Major
    Notes for Consumers: Discuss cannabis use with your care team. The effects of cannabis may be altered if used with your medication.
    Notes for Professionals: Advise patients to avoid cannabis use during apalutamide treatment. Concomitant use may decrease the concentration of some cannabinoids and alter their effects. The cannabinoids delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) are CYP3A substrates and apalutamide is a strong CYP3A inducer. Concomitant use of a cannabinoid product containing THC and CBD at an approximate 1:1 ratio with another strong CYP3A inducer decreased THC, 11-OH-THC, and CBD peak exposures by 36%, 87%, and 52% respectively.
  • Apalutamide 60mg, Oral tablet

    Interaction: Grapefruit juice
    Severity: Moderate
    Notes for Consumers: Side effects from Apalutamide may get worse if you drink grapefruit juice or eat grapefruit regularly. Contact your health care provider if you experience diarrhea, increased blood pressure, fatigue, nausea, joint pain, hot flashes, or other unusual effects.
    Notes for Professionals: The exposure to apalutamide may be significantly increased in patients who regularly consume grapefruit or grapefruit juice, a strong CYP3A4 inhibitor.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.