• Image of EVOTAZ medication Image of EVOTAZ medication

    • EVOTAZ

    • QTY 30
    • 300-150 MG
    • Tablet
    • Near  77381

ATAZANAVIR; COBICISTAT (at a za NA veer; koe BIS i stat) helps manage the symptoms of HIV infection. It works by limiting the spread of HIV in the body. This medication is not a cure for HIV or AIDS and it may still be possible to spread HIV to others while taking it. It does not prevent other sexually transmitted infections (STIs).

EVOTAZ Lifestyle Interactions

  • Atazanavir Sulfate 300mg, Cobicistat 150mg, Oral tablet

    • Interaction: Food
    • Severity: Major
    • Notes for Consumers: Do not take Atazanavir with Food high in calories or fat. It is best to take atazanavir with a light meal or snack. If you eat grapefruit or drink grapefruit juice, keep your consumption regular (do not drastically change your intake) and tell your health care provider that grapefruit is part of your diet.
    • Notes for Professionals: Atazanavir needs to be taken with a light snack or meal, such as dry toast with jelly, apple juice, and coffee with skim milk in order to enhance oral absorption. However, administration with food high in calories and fat can result in a decrease in the AUC of atazanavir.

  • Atazanavir Sulfate 300mg, Cobicistat 150mg, Oral tablet

    • Interaction: Cannabis
    • Severity: Major
    • Notes for Consumers: Discuss cannabis use with your care team. The effects of cannabis may be altered if used with your medication. Call emergency services right away if you experience slow or shallow breathing, shortness of breath, feeling faint, dizziness, confusion, or trouble staying awake.
    • Notes for Professionals: Advise patients to avoid cannabis use during protease inhibitor treatment. Concomitant use may alter the exposure of some cannabinoids and increase the risk for adverse reactions. The cannabinoids delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) are CYP3A substrates and protease inhibitors are strong CYP3A inhibitors. Concomitant use of a cannabinoid product containing THC and CBD at an approximate 1:1 ratio with another strong CYP3A inhibitor increased THC, 11-OH-THC, and CBD peak exposures by 1.3-, 3-, and 1.9-fold respectively.

  • Atazanavir Sulfate 300mg, Cobicistat 150mg, Oral tablet

    • Interaction: Grapefruit juice
    • Severity: Moderate
    • Notes for Consumers: Although an interaction is possible, these drugs can be used together with caution. You may experience more side effects. Report any new or unusual side effects to your health care professional.
    • Notes for Professionals: Caution is warranted when cobicistat is administered with grapefruit juice as there is a potential for elevated cobicistat concentrations. Grapefruit juice is a CYP3A4 and CYP2D6 inhibitor, while cobicistat is a substrate of CYP3A4 and CYP2D6.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.