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INVIRASE
- QTY 120
- 500 MG
- Tablet
- Near 77381
SAQUINAVIR (sa KWIN a veer) helps manage the symptoms of HIV infection. It works by limiting the spread of HIV in the body. This medication is not a cure for HIV or AIDS and it may still be possible to spread HIV to others while taking it. It does not prevent other sexually transmitted infections (STIs).
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INVIRASE
- QTY 120
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- Tablet
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INVIRASE
- QTY 120
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INVIRASE Lifestyle Interactions
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Saquinavir Mesylate 500mg, Oral tablet
• Interaction: Cannabis• Severity: Major• Notes for Consumers: Discuss cannabis use with your care team. The effects of cannabis may be altered if used with your medication. Call emergency services right away if you experience slow or shallow breathing, shortness of breath, feeling faint, dizziness, confusion, or trouble staying awake.• Notes for Professionals: Advise patients to avoid cannabis use during protease inhibitor treatment. Concomitant use may alter the exposure of some cannabinoids and increase the risk for adverse reactions. The cannabinoids delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) are CYP3A substrates and protease inhibitors are strong CYP3A inhibitors. Concomitant use of a cannabinoid product containing THC and CBD at an approximate 1:1 ratio with another strong CYP3A inhibitor increased THC, 11-OH-THC, and CBD peak exposures by 1.3-, 3-, and 1.9-fold respectively. -
Saquinavir Mesylate 500mg, Oral tablet
• Interaction: Grapefruit juice• Severity: Moderate• Notes for Consumers: Although an interaction is possible, in most patients it is not significant. Grapefruit juice and grapefruit-containing foods may increase the side effects of Saquinavir. Do not significantly alter grapefruit juice intake while taking this drug, or avoid grapefruit juice if possible.• Notes for Professionals: Saquinavir is metabolized via the cytochrome CYP3A4 isozyme. Grapefruit juice contains a compound that inhibits CYP3A4 in enterocytes in the GI tract. Saquinavir levels may increase; it is possible that saquinavir-induced side effects could be increased in some individuals. Individuals should not drastically alter their intake of grapefruit juice or should avoid concurrent use unless advised differently by their healthcare professional.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
