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ADO-TRASTUZUMAB EMTANSINE (ADD oh traz TOO zuh mab em TAN zine) treats breast cancer. It works by blocking a protein that causes cancer cells to grow and multiply. This helps to slow or stop the spread of cancer cells.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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This medication is infused into a vein. It is given by your care team in a hospital or clinic setting.
This medication is not approved for use in children.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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-Atazanavir
-Boceprevir
-Clarithromycin
-Dalfopristin; quinupristin
-Delavirdine
-Indinavir
-Isoniazid, INH
-Itraconazole
-Ketoconazole
-Nefazodone
-Nelfinavir
-Ritonavir
-Telaprevir
-Telithromycin
-Tipranavir
-Voriconazole
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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This medication may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your care team tells you to stop.
You may need blood work while taking this medication.
This medication may increase your risk to bruise or bleed. Call your care team if you notice any unusual bleeding.
Be careful brushing or flossing your teeth or using a toothpick because you may get an infection or bleed more easily. If you have any dental work done, tell your dentist you are receiving this medication.
Talk to your care team if you may be pregnant. Serious birth defects can occur if you take this medication during pregnancy and for 7 months after the last dose. You will need a negative pregnancy test before starting this medication. Contraception is recommended while taking this medication and for 7 months after the last dose. Your care team can help you find the option that works for you.
If your partner can get pregnant, use a condom during sex while taking this medication and for 4 months after the last dose.
Do not breastfeed while taking this medication and for 7 months after the last dose.
This medication may cause infertility. Talk to your care team if you are concerned with your fertility.
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Keep appointments for follow-up doses. It is important not to miss your dose. Call your care team if you are unable to keep an appointment.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Bleeding—bloody or black, tar-like stools, vomiting blood or brown material that looks like coffee grounds, red or dark brown urine, small red or purple spots on skin, unusual bruising or bleeding
-Dry cough, shortness of breath or trouble breathing
-Heart failure—shortness of breath, swelling of the ankles, feet, or hands, sudden weight gain, unusual weakness or fatigue
-Infusion reactions—chest pain, shortness of breath or trouble breathing, feeling faint or lightheaded
-Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
-Pain, tingling, or numbness in the hands or feet
-Painful swelling, warmth, or redness of the skin, blisters or sores at the infusion site
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
-Constipation
-Fatigue
-Headache
-Muscle pain
-Nausea
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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This medication is given in a hospital or clinic. It will not be stored at home.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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