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METOCLOPRAMIDE (met oh kloe PRA mide) treats reflux disease. It is prescribed when other medications have not worked. It may also be used to treat slow emptying of the digestive tract (gastroparesis). It works by helping the muscles in your digestive tract move food. This empties your digestive tract, which relieves symptoms such as fullness, nausea, and heartburn.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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Take this medication by mouth. Follow the directions on the prescription label. Take this medication at least 30 minutes before eating and at bedtime. Leave the tablet in the sealed blister pack until you are ready to take it. With dry hands, open the blister and gently remove the tablet. If the tablet breaks or crumbles, throw it away and take a new tablet out of the blister pack. Place the tablet in the mouth and allow it to dissolve, and then swallow. You do not need water to take this medication. Do not take your medication more often than directed.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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-Alcohol
-Antihistamines for allergy, cough, and cold
-Atovaquone
-Atropine
-Bupropion
-Certain medications for anxiety or sleep
-Certain medications for bladder problems, such as oxybutynin, tolterodine
-Certain medications for depression or mental health conditions
-Certain medications for Parkinson's disease
-Certain medications for seizures, such as phenobarbital, primidone
-Certain medications for stomach problems, such as dicyclomine, hyoscyamine
-Certain medications for travel sickness, such as scopolamine
-Cyclosporine
-Digoxin
-Fosfomycin
-General anesthetics, such as halothane, isoflurane, methoxyflurane, propofol
-Insulin and other medications for diabetes
-Ipratropium
-MAOIs, such as Carbex, Eldepryl, Marplan, Nardil, and Parnate
-Medications that relax muscles for surgery
-Opioid medications for pain
-Paroxetine
-Phenothiazines, such as chlorpromazine, mesoridazine, prochlorperazine, thioridazine
-Posaconazole
-Quinidine
-Sirolimus
-Tacrolimus
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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It may take a few weeks for your condition to improve. Do not take this medication for longer than 12 weeks. The longer you take this medication and the more that you take, the more likely you are to have side effects. If you are over 65 years of age, a female, or you have diabetes, you may be at increased risk for side effects. Contact your care team right away if you have movements that you cannot control such as lip smacking, rapid movements of the tongue, unusual movements of the eyes, head, or arms.
Patients and their families should watch out for worsening depression or thoughts of suicide. Also watch out for sudden changes in feelings such as feeling anxious, agitated, panicky, irritable, hostile, aggressive, impulsive, severely restless, overly excited and hyperactive, or not being able to sleep. If this happens, especially at the beginning of treatment or after a change in dose, call your care team.
Do not treat yourself for high fever. Ask your care team for advice.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medication affects you. Do not stand or sit up quickly, especially if you are over 65 years of age. This reduces the risk of dizzy or fainting spells. Avoid alcoholic drinks.
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If you miss a dose, skip it. Take your next dose at the normal time. Do not take extra or 2 doses at the same time to make up for the missed dose.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-High fever, stiff muscles, increased sweating, fast or irregular heartbeat, and confusion, which may be signs of neuroleptic malignant syndrome
-High prolactin level—unexpected breast tissue growth, discharge from the nipple, change in sex drive or performance, irregular menstrual cycle
-Increase in blood pressure
-Swelling of the ankles, hands, or feet
-Thoughts of suicide or self-harm, worsening mood, feelings of depression
-Uncontrolled and repetitive body movements, muscle stiffness or spasms, tremors or shaking, loss of balance or coordination, restlessness, shuffling walk, which may be signs of extrapyramidal symptoms (EPS)
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
-Dizziness
-Drowsiness
-Fatigue
-Headache
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused medication after the expiration date.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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