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    • NABUMETONE (Generic for RELAFEN)

    • QTY 60
    • 500 MG
    • Tablet
    • Near  77381

NABUMETONE (na BYOO me tone) treats arthritis. It works by decreasing pain and inflammation. It belongs to a group of medications called NSAIDs.


NABUMETONE (Generic for RELAFEN) Lifestyle Interactions

  • Rivaroxaban 20mg, Oral tablet

    Interaction: Grapefruit juice
    Severity: Major
    Notes for Consumers: Tell your health care professional that you drink Grapefruit Juice before you take Rivaroxaban. If you drink Grapefruit Juice and take Rivaroxaban, your risk of bleeding is increased. Immediately report any unusual bleeding or bruising.
    Notes for Professionals: Avoid concomitant administration of rivaroxaban and grapefruit juice; significant increases in rivaroxaban exposure may increase bleeding risk. Rivaroxaban is a substrate of CYP3A4/5 and the P-glycoprotein (P-gp) transporter. Grapefruit juice is a combined P-gp inhibitor and strong CYP3A4 inhibitor. Concurrent use of a single dose of rivaroxaban and ritonavir, a combined P-gp and strong CYP3A4 inhibitor, led to an increase in the steady-state rivaroxaban AUC by 150% and to an increase in Cmax by 60%. Similar increases in pharmacodynamic effects such as factor Xa inhibition and PT prolongation were also observed.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.