OMAVELOXOLONE (oh ma vel OX oh lone) treats Friedreich ataxia, a condition that causes movement problems. It works by helping to protect cells in the body. This decreases symptoms. It also improves the ability to engage in daily activities, such as speaking, standing, and walking.


SKYCLARYS Lifestyle Interactions

  • Omaveloxolone 50mg, Oral capsule

    Interaction: Grapefruit juice
    Severity: Major
    Notes for Consumers: Do not drink grapefruit juice or eat grapefruit while taking this medication. Grapefruit may alter the effects of your medication. Serious side effects may occur. Contact your care team right away if you experience new or worsening side effects.
    Notes for Professionals: Advise patients to avoid grapefruit and grapefruit juice during omaveloxolone treatment due to the risk of increased omaveloxolone exposure and adverse reactions. Omaveloxolone is a CYP3A substrate and grapefruit juice is a strong CYP3A inhibitor.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.