• Image of Tivdak medication Image of Tivdak medication
    • TIVDAK

    • QTY 1
    • 40 MG
    • VIAL
    • Near  77381

TISOTUMAB VEDOTIN (tye SOT ue mab ve DOE tin) treats cervical cancer. It works by blocking a protein that causes cancer cells to grow and multiply. This helps to slow or stop the spread of cancer cells.


TIVDAK Lifestyle Interactions

  • Tisotumab vedotin 40mg, Powder for solution for injection

    Interaction: Grapefruit juice
    Severity: Major
    Notes for Consumers: Do not drink grapefruit juice or eat grapefruit or grapefruit-containing foods while taking tisotumab vedotin. Side effects from tisotumab vedotin may get worse. Contact your prescriber immediately if you experience any new or unusual side effects.
    Notes for Professionals: Advise patients to avoid grapefruit juice while taking tisotumab vedotin due to the risk of increased exposure to monomethyl auristatin E (MMAE) which may increase the incidence and severity of adverse reactions. MMAE, the active component of tisotumab vedotin, is a CYP3A substrate and grapefruit juice is a strong CYP3A4 inhibitor. Strong CYP3A4 inhibitors are predicted to increase the exposure of MMAE by 34%.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.