-
COLLAGENASE (kohl LAH jen ace) treats conditions caused by thickening of tissue in your body. It works by breaking down excess collagen in the tissue, which reduces stiffness and tightness.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
-
This medication is injected into the affected area. It is given by your care team in a hospital or clinic setting.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
-
-Aspirin and aspirin-like medications
-Certain medications that treat or prevent blood clots, such as warfarin, enoxaparin, dalteparin, apixaban, dabigatran, rivaroxaban
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
-
Your condition will be monitored carefully while you are receiving this medication.
If medication is for Dupuytren's Contracture, visit your care team 1 to 3 days after the injection. Until you visit your care team, do not flex or extend the fingers of your hand that was injected. Do not touch your finger that was injected. Elevate your hand until bedtime. Do not perform activity with the injected hand until you are told that it is ok. Follow any instructions about wearing a splint or performing finger exercises. Contact your care team as soon as possible if you get increasing redness or swelling in the hand, have numbness or tingling in the treated finger, or have trouble bending the finger after the swelling goes down.
If medication is for Peyronie's disease, do not have sex between the first and second injections. Wait 4 weeks after the second injection and when there is no more pain or swelling in the penis to have sex. Avoid using vacuum erection devices during treatment with this medication. Try to avoid straining stomach muscles such as during bowel movements. Your care team will give you instructions on how to perform modeling activities at home. Contact your care team as soon as possible if you have severe pain or swelling in the penis, severe purple bruising and swelling of the penis, trouble passing urine, blood in urine, popping or cracking sound form the penis, or sudden loss of ability to maintain an erection.
-
Keep appointments for follow-up doses. It is important not to miss your dose. Call your care team if you are unable to keep an appointment.
-
Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Feeling faint or lightheaded
-Skin infection—skin redness, swelling, warmth, or pain
-Severe back pain, chest pain, headache, trouble breathing after injection
-Snap or pop that you feel or hear, severe pain, numbness, swelling, or bruising of or trouble moving in area where injected
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
-Pain, redness, or irritation at injection site
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
-
This medication is given in a hospital or clinic. It will not be stored at home.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
En Español
