VANZACAFTOR; TEZACAFTOR; DEUTIVACAFTOR (VAN zah KAF tor; TEZ a KAF tor; due TIV a KAF tor) treats cystic fibrosis (CF). It works by helping your body balance the level of salt and water in your lungs. This prevents the buildup of mucus and reduces the symptoms of CF.

ALYFTREK Lifestyle Interactions

  • Vanzacaftor 10mg, Tezacaftor 50mg, Deutivacaftor 125mg, Oral tablet

    • Interaction: Grapefruit juice
    • Severity: Major
    • Notes for Consumers: Do not take these agents together. Side effects from tezacaftor; ivacaftor may get worse if you take these agents together. These include dark yellow or brown urine, general ill feeling or flu-like symptoms, light-colored stools, loss of appetite, nausea, right upper belly pain, unusually weak or tired, yellowing of the eyes and skin.
    • Notes for Professionals: Avoid food or drink containing grapefruit juice or Seville oranges during treatment with tezacaftor; ivacaftor. Grapefruit contains one or more components that inhibit CYP3A; both tezacaftor and ivacaftor are CYP3A substrates (ivacaftor is a sensitive substrate).

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.