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VUTRISIRAN (vue TRI sir AN) treats nerve pain, tingling, or numbness in the hands or feet in people with transthyretin amyloidosis (ATTR). It may also be used to lower the risk of worsening disease and death caused by cardiomyopathy. It works by decreasing the buildup of a protein that causes nerve injury and thickening of the heart muscle. This decreases symptoms. It also makes it easier for your heart to pump blood to the rest of your body.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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This medication is injected under the skin. It is given by your care team in a hospital or clinic setting.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Interactions are not expected.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse. Your condition will be monitored carefully while you are receiving this medication.
Tell your care team right away if you have any change in your eyesight.
You should make sure you get enough vitamin A while you are taking this medication. Discuss the foods you eat and the vitamins you take with your care team.
Women should inform their care team if they wish to become pregnant or think they might be pregnant. Talk to your care team for more information.
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Keep appointments for follow-up doses. It is important not to miss your dose. Call your care team if you are unable to keep an appointment.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Low vitamin A level—change in vision, dry eyes, dry skin, frequent infections
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
-Joint pain
-Pain, redness, or irritation at injection site
-Pain in the hands or feet
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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This medication is given in a hospital or clinic. It will not be stored at home.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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