-
APREPITANT (ap RE pi tant) prevents nausea and vomiting from chemotherapy. It works by blocking substances in your body that may cause nausea and vomiting. It belongs to a group of medications called antiemetics.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
-
Take this medication by mouth with a glass of water. Follow the directions on the prescription label. Usually, you will take your first dose one hour before your chemotherapy begins, and then once daily in the morning for the next 2 days after your chemotherapy treatment. This medication may be taken with or without food. Do not take more often than directed.
Talk to your care team about the use of this medication in children. While this medication may be prescribed for children as young as 12 years for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
-
Do not take this medication with any of the following:
-Cisapride
-Flibanserin
-Lomitapide
-Pimozide
This medication may also interact with the following:
-Diltiazem
-Estrogen and progestin hormones
-Medications for fungal infections, such as ketoconazole or itraconazole
-Medications for HIV
-Medications for seizures or to control epilepsy, such as carbamazepine or phenytoin
-Medications used for sleep or anxiety disorders, such as alprazolam, diazepam, midazolam
-Nefazodone
-Paroxetine
-Ranolazine
-Rifampin
-Some chemotherapy medications, such as etoposide, ifosfamide, vinblastine, vincristine
-Some antibiotics, such as clarithromycin, erythromycin, troleandomycin
-Steroid medications, such as dexamethasone or methylprednisolone
-Tolbutamide
-Warfarin
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
-
Visit your care team for regular checks on your progress.
Do not take this medication if you already have nausea and vomiting. Ask your care team what to do if you already have nausea.
Estrogen and progestin hormones may not work as well while you are taking this medication. Contraception is recommended while taking this medication and for 1 month after the last dose. Talk to your care team about contraceptive options. They can help you find the option that works for you.
This medication should not be used continuously for a long time.
This medication may change your liver function blood test results.
-
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
-
Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
-Diarrhea
-Dizziness
-Headache
-Hiccups
-Unusual weakness or fatigue
-Upset stomach
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
-
Keep out of the reach of children.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused medication after the expiration date.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
En Español
