BEIZRAY

DOCETAXEL (doe se TAX el) treats some types of cancer. It works by slowing down the growth of cancer cells.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

This medication is infused into a vein. It is given by your care team in a hospital or clinic setting.
Talk to your care team about the use of this medication in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.

Do not take this medication with any of the following:
-Live virus vaccines
This medication may also interact with the following:
-Certain antibiotics, such as clarithromycin, telithromycin
-Certain antivirals for HIV or hepatitis
-Certain medications for fungal infections, such as itraconazole, ketoconazole, voriconazole
-Grapefruit juice
-Nefazodone
-Supplements, such as St. John's wort

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

This medication may make you feel generally unwell. This is not uncommon as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your care team tells you to stop.
You may need blood work done while you are taking this medication.
This medication can cause serious side effects and infusion reactions. To reduce the risk, your care team may give you other medications to take before receiving this one. Be sure to follow the directions from your care team.
This medication may increase your risk of getting an infection. Call your care team for advice if you get a fever, chills, sore throat, or other symptoms of a cold or flu. Do not treat yourself. Try to avoid being around people who are sick.
Avoid taking medications that contain aspirin, acetaminophen, ibuprofen, naproxen, or ketoprofen unless instructed by your care team. These medications may hide a fever.
Be careful brushing or flossing your teeth or using a toothpick because you may get an infection or bleed more easily. If you have any dental work done, tell your dentist you are receiving this medication.
Some products may contain alcohol. Ask your care team if this medication contains alcohol. Be sure to tell all care teams you are taking this medicine. Certain medications, like metronidazole and disulfiram, can cause an unpleasant reaction when taken with alcohol. The reaction includes flushing, headache, nausea, vomiting, sweating, and increased thirst. The reaction can last from 30 minutes to several hours.
This medication may affect your coordination, reaction time, or judgement. Do not drive or operate machinery until you know how this medication affects you. Sit up or stand slowly to reduce the risk of dizzy or fainting spells. Drinking alcohol with this medication can increase the risk of these side effects.
Talk to your care team about your risk of cancer. You may be more at risk for certain types of cancer if you take this medication.
Talk to your care team if you wish to become pregnant or think you might be pregnant. This medication can cause serious birth defects if taken during pregnancy or if you get pregnant within 2 months after stopping therapy. A negative pregnancy test is required before starting this medication. A reliable form of contraception is recommended while taking this medication and for 2 months after stopping it. Talk to your care team about reliable forms of contraception.
Do not breast-feed while taking this medication and for 1 week after stopping therapy.
Use a condom during sex and for 4 months after stopping therapy. Tell your care team right away if you think your partner might be pregnant. This medication can cause serious birth defects.
This medication may cause infertility. Talk to your care team if you are concerned about your fertility.

Keep appointments for follow-up doses. It is important not to miss your dose. Call your care team if you are unable to keep an appointment.

Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Change in vision such as blurry vision, seeing halos around lights, vision loss
-Infection—fever, chills, cough, or sore throat
-Infusion reactions—chest pain, shortness of breath or trouble breathing, feeling faint or lightheaded
-Low red blood cell level—unusual weakness or fatigue, dizziness, headache, trouble breathing
-Pain, tingling, or numbness in the hands or feet
-Painful swelling, warmth, or redness of the skin, blisters or sores at the infusion site
-Redness, blistering, peeling, or loosening of the skin, including inside the mouth
-Sudden or severe stomach pain, bloody diarrhea, fever, nausea, vomiting
-Swelling of the ankles, hands, or feet
-Tumor lysis syndrome (TLS)—nausea, vomiting, diarrhea, decrease in the amount of urine, dark urine, unusual weakness or fatigue, confusion, muscle pain or cramps, fast or irregular heartbeat, joint pain
-Unusual bruising or bleeding
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
-Change in nail shape, thickness, or color
-Change in taste
-Hair loss
-Increased tears

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

This medication is given in a hospital or clinic. It will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.