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CAPLACIZUMAB (kap la SIZ ue mab) treats acquired thrombotic thrombocytopenic purpura (aTTP), a condition that causes blood clots and low levels of platelets in the body. It works by preventing blood cells (platelets) from clumping together to form a clot. It is a monoclonal antibody.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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This medication is injected into a vein or under the skin. It is usually given by a care team in a hospital or clinic setting. It may also be given at home.
If you get this medication at home, you will be taught how to prepare and give it. Take it as directed on the prescription label at the same time every day. Keep taking it unless your care team tells you to stop.
It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or care team to get one.
This medication comes with INSTRUCTIONS FOR USE. Ask your pharmacist for directions on how to use this medication. Read the information carefully. Talk to your pharmacist or care team if you have questions.
Talk to your care team about the use of this medication in children. While it may be prescribed for children as young as 12 years for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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-Blood thinners, such as warfarin, heparin, enoxaparin, dalteparin, apixaban, rivaroxaban
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.
If you are going to need surgery or a procedure, tell your care team that you are taking this medication.
Tell your dentist and dental surgeon that you are taking this medication. You should not have major dental surgery while on this medication. See your dentist to have a dental exam and fix any dental problems before starting this medication. Take good care of your teeth while on this medication. Make sure you see your dentist for regular follow-up appointments.
Talk to your care team if you may be pregnant. Serious fetal side effects, such as bleeding, can occur if you take this medication during pregnancy. There are benefits and risks to taking medications during pregnancy. Your care team can help you find the option that works for you.
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If you miss a dose, take it as soon as you can unless it is more than 12 hours late. If it is more than 12 hours late, skip that dose. Take your next dose at the normal time. Do not take double or extra doses.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Bleeding—bloody or black, tar-like stools, vomiting blood or brown material that looks like coffee grounds, red or dark brown urine, small red or purple spots on skin, unusual bruising or bleeding
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
-Back pain
-Bleeding from the nose or gums that won't stop
-Fatigue
-Headache
-Muscle pain
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children and pets.
Store in a refrigerator or at room temperature up to 30 degrees C (86 degrees F). Keep this medication in the original carton. Protect from light.
Refrigeration (preferred): Store in the refrigerator. Do not freeze. Get rid of any unused medication after the expiration date.
Room Temperature: This medication may be stored at room temperature for up to 2 months. Do not return it to the refrigerator. Get rid of any unused medication after 2 months or after it expires, whichever is first.
To get rid of medications that are no longer needed or have expired:
-Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medication, ask your pharmacist or care team how to get rid of this medication safely.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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