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GLASDEGIB (glas DEG ib) treats leukemia. It works by blocking a protein that causes cancer cells to grow and multiply. This helps to slow or stop the spread of cancer cells.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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Take this medication by mouth with water. Take it as directed on the prescription label at the same time every day. Do not cut, crush, or chew this medication. Swallow the tablets whole. You can take it with or without food. If it upsets your stomach, take it with food. Do not take it more often than directed. Your care team may change your dose or tell you to stop taking this medication if you get side effects. Do not change your dose or stop taking it unless your care team tells you to.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Do not take this medication with any of the following:
-Cisapride
-Dengue vaccine
-Dronedarone
-Pimozide
-Some medications for fungal infections, such as fluconazole, ketoconazole, posaconazole
-Thioridazine
This medication may also interact with the following:
-Grapefruit and foods or drinks that contain grapefruit
-Other medications that cause heart rhythm changes
-St. John's wort
Other medications may affect the way this medication works. Talk with your care team about all the medications you take. They may suggest changes to your treatment plan to lower the risk of side effects and to make sure your medications work as intended.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Visit your care team for regular checks on your progress. It may be some time before you see the benefit from this medication.
You may need blood work while taking this medication.
Talk to your care team if you wish to become pregnant or think you might be pregnant. This medication can cause serious birth defects if taken during pregnancy or for 30 days after the last dose. A reliable form of contraception is recommended while taking this medication and for 30 days after the last dose. Do not father a child while taking this medication or for 30 days after the last dose. A barrier contraceptive, such as a condom, is recommended. Talk to your care team about reliable forms of contraception.
Do not breast-feed while taking this medication and for 30 days after the last dose.
Do not donate sperm while taking this medication or for 30 days after the last dose.
This medication may cause infertility. Talk to your care team if you are concerned about your fertility.
Do not donate blood while you are taking this medication or for 30 days after the last dose. Donated blood may contain enough of this medication to cause birth defects in a fetus if transfused to someone who is pregnant.
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If you miss a dose, take it as soon as you can unless it is less than 12 hours before the next dose. If it is less than 12 hours before the next dose, skip the missed dose. Take the next dose at the normal time.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Bleeding—bloody or black, tar-like stools, vomiting blood or brown material that looks like coffee grounds, red or dark brown urine, small red or purple spots on skin, unusual bruising or bleeding
-Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing
-Infection—fever, chills, cough, or sore throat
-Low red blood cell level—unusual weakness or fatigue, dizziness, headache, trouble breathing
-Muscle injury—unusual weakness or fatigue, muscle pain, dark yellow or brown urine, decrease in amount of urine
-Unusual bruising or bleeding
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
-Change in taste
-Loss of appetite
-Joint pain
-Nausea
-Pain, redness, or swelling with sores inside the mouth or throat
-Swelling of the ankles, hands, or feet
-Unusual weakness or fatigue
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or have expired:
-Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medication, ask your pharmacist or care team how to get rid of this medication.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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