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ERGOTAMINE (er GOT a meen) treats migraines. It works by blocking pain signals and narrowing blood vessels in the brain. It belongs to a group of medications called ergot alkaloids. It is not used to prevent migraines.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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Take this medication by mouth. Place the tablet under the tongue and allow it to completely dissolve. Do NOT chew or swallow the tablet. Follow the directions on the prescription label. For best results take this medication at the start of a migraine headache. Do not take this medication every day. Do not take your medication more often than directed.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Do not take this medication with any of the following:
-Adagrasib
-Bromocriptine
-Ceritinib
-Certain antibiotics, such as clarithromycin or erythromycin
-Certain antivirals for HIV or hepatitis
-Certain medications for blood pressure, heart disease, irregular heart beat
-Certain medications for fungal infections, such as itraconazole, ketoconazole, posaconazole, voriconazole
-Certain medications for migraine headache, such as almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan
-Cocaine
-Idelalisib
-Imatinib
-Levoketoconazole
-Lonafarnib
-Mifepristone
-Pseudoephedrine
-Ribociclib
-Tucatinib
This medication may also interact with the following:
-Certain medications for depression, anxiety, or mental health conditions
-Clotrimazole
-Fluconazole
-Grapefruit juice
-Metronidazole
-Nicotine
-Propranolol
-Zileuton
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Visit your care team for regular checks on your progress. Check with your care team if you do not get relief from your headaches after using this medication. You may need to be changed to a different kind of medication to treat your headaches.
This medication may affect your coordination, reaction time, or judgment. Do not drive or operate machinery until you know how this medication affects you. Sit up or stand slowly to reduce the risk of dizzy or fainting spells. Drinking alcohol with this medication can increase the risk of these side effects.
Tell your care team right away if you notice unexplained wounds on your fingers or toes while taking this medication. You should also tell your care team if you experience numbness or pain, changes in skin color, or sensitivity to temperature in your fingers or toes.
If you take migraine medications for 10 or more days a month, your migraines may get worse. Keep a diary of headache days and medication use. Contact your care team if your migraine attacks occur more frequently.
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This does not apply; this medication is not for regular use.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Burning, pain, tingling, or color changes in the hands, arms, legs, or feet
-Heart attack—pain or tightness in the chest, shoulders, arms, or jaw, nausea, shortness of breath, cold or clammy skin, feeling faint or lightheaded
-Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing
-Increase in blood pressure
-Raynaud syndrome—cool, numb, or painful fingers or toes that may change color from pale, to blue, to red
-Seizures
-Stroke—sudden numbness or weakness of the face, arm, or leg, trouble speaking, confusion, trouble walking, loss of balance or coordination, dizziness, severe headache, change in vision
-Sudden or severe stomach pain, bloody diarrhea, fever, nausea, vomiting
-Vision loss
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
-Dizziness
-General discomfort and fatigue
-Nausea
-Vomiting
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep in foil package until ready to use. Protect from light and moisture. Throw away any unused medication after the expiration date.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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