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LETROZOLE (LET roe zole) treats some types of breast cancer. It works by decreasing the amount of estrogen hormone your body makes, which slows or stops breast cancer cells from spreading or growing.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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Take this medication by mouth with a glass of water. You may take it with or without food. Follow the directions on the prescription label. Take your medication at regular intervals. Do not take your medication more often than directed. Do not stop taking except on your care team's advice.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Do not take this medication with any of the following:
-Estrogen and progestin hormones
This medication may also interact with the following:
-Dietary supplements, such as androstenedione or DHEA
-Prasterone
-Tamoxifen
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.
You may need blood work done while you are taking this medication.
This medication may affect your coordination, reaction time, or judgment. Do not drive or operate machinery until you know how this medication affects you. Sit up or stand slowly to reduce the risk of dizzy or fainting spells.
Using this medication for a long time may weaken your bones. The risk of bone fractures may be increased. Talk to your care team about your bone health.
Talk to your care team if you may be pregnant. Serious fetal side effects can occur if you take this medication during pregnancy and for 3 weeks after the last dose. When taken as part of fertility treatment, it is not likely to cause fetal side effects. You will need a negative pregnancy test before starting this medication. Contraception is recommended while taking this medication and for 3 weeks after the last dose. Your care team can help you find the option that works for you.
Do not breastfeed while taking this medication and for at least 3 weeks after the last dose.
This medication may cause infertility. Talk to your care team if you are concerned about your fertility.
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If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
-Dizziness
-Fatigue
-Headache
-Hot flashes
-Joint Pain
-Swelling of the ankles, hands, or feet
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or have expired:
-Take the medication to a take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, empty the medication out of the container. Mix it with cat litter, dirt, coffee grounds, or another unwanted substance. Seal the mixture in a bag or container. Put it in the trash.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.