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PIMOZIDE (PI moe zide) manages the symptoms of Tourette disorder. It is prescribed when other medications have not worked or cannot be tolerated. It works by reducing vocal and motor tics. This improves the ability to engage in daily activities. It belongs to a group of medications called antipsychotics. Antipsychotic medications can be used to treat several kinds of mental health conditions.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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Take this medication by mouth with a glass of water. Follow the directions on the prescription label. Do not take with grapefruit juice. Take your doses at regular intervals. Do not take your medication more often than directed. Do not stop taking except on the advice of your care team.
Talk to your care team about the use of this medication in children. While this medication may be prescribed for children as young as 12 years for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Do not take this medication with any of the following:
-Other medications that cause heart rhythm changes
-Some antibiotics, such as azithromycin, clarithromycin, erythromycin
-Some antivirals for HIV or hepatitis, such as nelfinavir, ritonavir, saquinavir
-Some medications for depression, such as citalopram, escitalopram, fluvoxamine, nefazodone, paroxetine, sertraline
-Some medications for fungal infections, such as itraconazole or ketoconazole
This medication may also interact with the following:
-Alcohol
-Areca nut (betel nut)
-Benzodiazepines, such as alprazolam, diazepam, lorazepam
-Grapefruit and foods or drinks that contain grapefruit
-Medications that cause drowsiness before a procedure, such as propofol
-Medications that help you fall asleep
-Medications that relax muscles
-Opioids for pain or cough
-Phenothiazines, such as chlorpromazine, prochlorperazine, thioridazine
-Some antihistamines
-Some medications for nerve pain, such as gabapentin or pregabalin
-Some medications for seizures, such as phenobarbital or primidone
-Zileuton
Other medications may affect the way this medication works. Talk with your care team about all the medications you take. They may suggest changes to your treatment plan to lower the risk of side effects and to make sure your medications work as intended.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Visit your care team for regular checks on your progress. Tell your care team if symptoms do not start to get better or if they get worse. Do not stop taking except on your care team's advice.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medication affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can increase dizziness and drowsiness. Avoid alcoholic drinks.
This medication may increase blood sugar. Ask your care team if changes in diet or medications are needed if you have diabetes.
This medication can cause problems with controlling your body temperature. It can lower the response of your body to cold temperatures. If possible, stay indoors during cold weather. If you must go outdoors, wear warm clothes. It can also lower the response of your body to heat. Do not overheat. Do not over-exercise. Stay out of the sun when possible. If you must be in the sun, wear cool clothing. Drink plenty of water. If you have trouble controlling your body temperature, call your care team right away.
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If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing
-High fever, stiff muscles, increased sweating, fast or irregular heartbeat, and confusion, which may be signs of neuroleptic malignant syndrome
-Infection—fever, chills, cough, or sore throat
-Uncontrolled and repetitive body movements, muscle stiffness or spasms, tremors or shaking, loss of balance or coordination, restlessness, shuffling walk, which may be signs of extrapyramidal symptoms (EPS)
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
-Constipation
-Dizziness
-Drowsiness
-Dry mouth
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medication after the expiration date.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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