• Image of Migergot medication Image of Migergot medication
    • MIGERGOT

    • QTY 12
    • 2-100MG
    • SUPP.RECT
    • Near  77381

ERGOTAMINE; CAFFEINE (er GOT a meen; KAF een) treats migraines. It works by blocking pain signals and narrowing blood vessels in the brain. It is a combination of an ergot alkaloid and caffeine. It is not used to prevent migraines.


MIGERGOT Lifestyle Interactions

  • Ergotamine Tartrate 2mg, Caffeine 100mg, Caffeine, Anhydrous 100mg, Rectal suppository

    Interaction: Tobacco
    Severity: Major
    Notes for Consumers: Do not smoke or use tobacco products while taking this medication. When used together, your medication may not work as well for you.
    Notes for Professionals: Advise patients who are taking caffeine to avoid smoking tobacco. Smoking tobacco has been observed to increase caffeine clearance by 50% to 70%. Caffeine is a CYP1A2 substrate and smoking tobacco induces CYP1A2.
  • Ergotamine Tartrate 2mg, Caffeine 100mg, Caffeine, Anhydrous 100mg, Rectal suppository

    Interaction: Grapefruit juice
    Severity: Major
    Notes for Consumers: Do not drink grapefruit juice or eat grapefruit while taking this medication. Grapefruit may alter the effects of your medication. Serious side effects may occur. Contact your care team right away if you experience new or worsening side effects.
    Notes for Professionals: Advise patients to avoid grapefruit and grapefruit juice during ergotamine treatment due to the risk for increased ergotamine exposure and adverse reactions. Ergotamine is a CYP3A substrate and grapefruit juice is a CYP3A inhibitor.
  • Ergotamine Tartrate 2mg, Caffeine 100mg, Caffeine, Anhydrous 100mg, Rectal suppository

    Interaction: Caffeine-containing Foods/Beverages
    Severity: Moderate
    Notes for Consumers: While taking Caffeine-containing medicines, limit the use of foods, beverages (examples: coffee, tea, colas), herbs (examples: guarana, green tea) and other products that contain additional caffeine, such as chocolate and some non-prescription medications or dietary supplements for headache, insomnia, or weight loss. Too much Caffeine can cause effects like nausea, nervousness, or sleeplessness. Some drug products for adults that contain caffeine have about as much caffeine as a cup of coffee.
    Notes for Professionals: Certain foods that contain high amounts of caffeine or theobromine should be limited during the therapeutic use of caffeine in order to limit additive methylxanthine effects. While taking Caffeine-containing medicines, limit the use of foods, beverages (examples: coffee, tea, colas), herbs (examples: guarana, green tea) and other products that contain additional caffeine, such as chocolate and some non-prescription medications or dietary supplements for headache, insomnia, or weight loss. Too much Caffeine can cause effects like nausea, nervousness, or sleeplessness. Some drug products for adults that contain caffeine have about as much caffeine as a cup of coffee.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.