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AMOXICILLIN; CLARITHROMYCIN; OMEPRAZOLE (a mox i SIL in; kla RITH roe mye sin; oh ME pra zol) treats ulcers caused by H. pylori bacteria. Omeprazole works by reducing the amount of acid in the stomach. Clarithromycin and amoxicillin kill or prevent the growth of bacteria. It is a combination of a PPI, a macrolide antibiotic, and a penicillin antibiotic.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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Take these medications by mouth with a full glass of water. Each dose should be taken twice per day before eating. Follow the directions on the prescription label. Swallow the capsules and tablets whole. Do not crush or chew. Take your doses at regular intervals. Do not take your medication more often than directed. Do not skip doses or stop your medication early even if you feel better. Do not stop taking except on your care team's advice.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Do not take this medication with any of the following:
-Atazanavir
-Cisapride
-Colchicine
-Dihydroergotamine
-Ergotamine
-Some heart medications like amiodarone, bepridil, dofetilide, droperidol, flecainide, ibutilide, procainamide, quinidine, sotalol
-Some medications for cholesterol like cerivastatin, lovastatin, simvastatin
-Medications for sleep or anxiety, like alprazolam, triazolam or midazolam
-Naloxegol
-Nelfinavir
-Pimozide
-Red yeast rice
-Rifampin
-St. John's Wort
This medication may also interact with the following:
-Carbamazepine
-Cilostazol
-Cyclosporine
-Digoxin
-Diltiazem
-Disulfiram
-Female hormones, like estrogens or progestins and birth control pills
-Iron supplements
-Other antibiotics
-Other medications for depression, sleep or psychotic disturbances
-Probenecid
-Sildenafil
-Some medications for fungal infections like itraconazole, ketoconazole
-Some medications for HIV-infection or AIDS
-Tacrolimus
-Theophylline
-Warfarin
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Visit your care team for regular check-ups. Tell your care team if your symptoms do not improve or if they get worse.
This medication may cause serious skin reactions. They can happen weeks to months after starting the medication. Contact your care team right away if you notice fevers or flu-like symptoms with a rash. The rash may be red or purple and then turn into blisters or peeling of the skin. Or, you might notice a red rash with swelling of the face, lips or lymph nodes in your neck or under your arms.
Call your care team as soon as you can if you get a fever, watery diarrhea, stomach pain, or vomiting. These could be symptoms of a more serious illness. Do not treat yourself. Call your care team for advice.
Estrogen or progestin hormones may not work properly while you are taking this medication. Talk to your care team about using an extra method of contraception.
If you are diabetic, you may get a false-positive result for sugar in your urine. Talk to your care team.
This medication may cause a decrease in vitamin B12. You should make sure that you get enough vitamin B12 while you are taking this medication. Discuss the foods you eat and the vitamins you take with your care team.
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If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Kidney injury—decrease in the amount of urine, swelling of the ankles, hands, or feet
-Lupus-like syndrome—joint pain, swelling, or stiffness, butterfly-shaped rash on the face, rashes that get worse in the sun, fever, unusual weakness or fatigue
-Redness, blistering, peeling, or loosening of the skin, including inside the mouth
-Severe diarrhea, fever
-Severe or prolonged vomiting or diarrhea
-Unusual vaginal discharge, itching, or odor
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
-Change in taste
-Diarrhea
-Headache
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from light and moisture. Throw away any unused medication after the expiration date.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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