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OMEPRAZOLE; SODIUM BICARBONATE (oh ME pray zol; SOE dee um bye KAR bon ate) treats heartburn, stomach ulcers, reflux disease, or other conditions caused by too much stomach acid. It works by reducing the amount of acid in the stomach. It is a combination of a PPI and an antacid.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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Take this medication by mouth with a glass of water. Do not take with any other liquids. Follow the directions on the prescription label. Do not cut, crush or chew this medication. Swallow the capsules whole. Take this medication on an empty stomach, at least 1 hour before a meal. Take your medication at regular intervals. Do not take your medication more often than directed. Do not stop taking except on your care team's advice.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Do not take this medication with any of the following:
-Atazanavir
-Clopidogrel
-Nelfinavir
-Rilpivirine
This medication may also interact with the following:
-Antifungals, such as itraconazole, ketoconazole, and voriconazole
-Certain antivirals for HIV or hepatitis
-Certain medications that treat or prevent blood clots, such as warfarin
-Cilostazol
-Citalopram
-Cyclosporine
-Dasatinib
-Digoxin
-Disfulfiram
-Diuretics
-Erlotinib
-Iron supplements
-Medications for anxiety, panic, and sleep, such as diazepam
-Medications for seizures, such as carbamazepine, phenobarbital, phenytoin
-Methotrexate
-Mycophenolate mofetil
-Nilotinib
-Rifampin
-St. John's Wort
-Tacrolimus
-Vitamin B12
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse. You may need blood work done while taking this medication.
This medication may cause a decrease in vitamin B12. You should make sure that you get enough vitamin B12 while you are taking this medication. Discuss the foods you eat and the vitamins you take with your care team.
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If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-High bicarbonate level—confusion, tremors or shaking, feeling faint or lightheaded, nausea, vomiting, muscle spasms, numbness of the face, feet, or hands
-Kidney injury—decrease in the amount of urine, swelling of the ankles, hands, or feet
-Low magnesium level—muscle pain or cramps, unusual weakness or fatigue, fast or irregular heartbeat, tremors
-Low vitamin B12 level—pain, tingling, or numbness in the hands or feet, muscle weakness, dizziness, confusion, trouble concentrating
-Rash on the cheeks or arms that gets worse in the sun
-Redness, blistering, peeling, or loosening of the skin, including inside the mouth
-Severe diarrhea, fever
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
-Gas
-Headache
-Nausea
-Stomach pain
-Vomiting
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children and pets.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture. Throw away any unused medication after the expiration date.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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