• Image of PROMETRIUM medication Image of PROMETRIUM medication
    • PROMETRIUM (Brand for PROGESTERONE)

    • QTY 90
    • 100 MG
    • Capsule
    • Near  33101

PROGESTERONE (proe JES ter one) prevents the lining of the uterus from becoming too thick in people taking estrogen after menopause. It may also be used to treat irregular menstrual cycles. It works by increasing levels of the hormone progesterone in your body. This medication is a progestin hormone.


PROMETRIUM (Brand for PROGESTERONE) Lifestyle Interactions

  • Progesterone 100mg, Oral capsule

    Interaction: Grapefruit juice
    Severity: Major
    Notes for Consumers: Do not drink grapefruit juice or eat grapefruit while taking this medication. Grapefruit may alter the effects of your medication. Serious side effects may occur. Contact your care team right away if you experience new or worsening side effects.
    Notes for Professionals: Advise patients to avoid grapefruit and grapefruit juice during progesterone treatment due to the risk for increased progesterone exposure and adverse reactions. Progesterone is a CYP3A substrate and grapefruit juice is a CYP3A inhibitor. Vaginal preparations of progesterone are not expected to interact.
  • Progesterone 100mg, Oral capsule

    Interaction: High Fat Foods
    Severity: Mild
    Notes for Consumers: In general, there are no food interactions of concern. Progesterone capsules are often taken with food, but do not need to be taken with food.
    Notes for Professionals: Food can increase the bioavailability of progesterone administered orally.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.