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REPAGLINIDE (re PAG lin ide) treats type 2 diabetes. It works by increasing insulin levels in your body, which decreases your blood sugar (glucose). Changes to diet and exercise are often combined with this medication.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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Take this medication by mouth with water. Take it as directed on the prescription label. Take it with food at the start of a meal. It should be taken no earlier than 30 minutes before meals. If a meal is skipped, skip the dose for that meal. Keep taking it unless your care team tells you to stop. Do not take it more often than directed.
Talk to your care team about the use of this medication in children. Special care may be needed.
People 65 years and older may have a stronger reaction and need a smaller dose.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Do not take this medication with any of the following:
-Gemfibrozil
This medication may also interact with the following:
-Certain supplements, such as chromium
-Clopidogrel
-Cyclosporine
Medications that may affect your blood sugar include:
-Alcohol
-Aspirin and aspirin-like medications
-Certain medications for allergies, asthma, cold, or cough
-Certain antibiotics, such as ciprofloxacin, isoniazid, levofloxacin, sulfamethoxazole; trimethoprim
-Certain antivirals for HIV or hepatitis
-Certain medications for blood pressure or heart disease
-Certain medications for mental health conditions, such as fluoxetine or olanzapine
-Certain medications for weight loss
-Diuretics, such as hydrochlorothiazide (HCTZ)
-Estrogen and progestin hormones
-Fenofibrate
-Gemfibrozil
-Lanreotide
-MAOIs, such as Carbex, Eldepryl, Marplan, Nardil, and Parnate
-Niacin
-Octreotide
-Pasireotide
-Pentamidine
-Phenytoin
-Steroid medications, such as prednisone or cortisone
-Testosterone
-Thyroid hormones
Medications that may mask the symptoms of low blood sugar include:
-Beta blockers, such as metoprolol and propranolol
-Clonidine
-Guanethidine
-Reserpine
Other medications may affect the way this medication works. Talk with your care team about all the medications you take. They may suggest changes to your treatment plan to lower the risk of side effects and to make sure your medications work as intended.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Visit your care team for regular checks on your progress.
A test called the HbA1C (A1C) will be monitored. This is a simple blood test. It measures your blood sugar control over the last 2 to 3 months. You will receive this test every 3 to 6 months.
Learn how to check your blood sugar. Learn the symptoms of low and high blood sugar and how to manage them.
Always carry a quick-source of sugar with you in case you have symptoms of low blood sugar. Examples include hard sugar candy or glucose tablets. Make sure others know that you can choke if you eat or drink when you develop serious symptoms of low blood sugar, such as seizures or unconsciousness. They must get medical help at once.
Tell your care team if you have high blood sugar. You might need to change the dose of your medication. If you are sick or exercising more than usual, you might need to change the dose of your medication.
Do not skip meals. Ask your care team if you should avoid alcohol. Many nonprescription cough and cold products contain sugar or alcohol. These can affect blood sugar.
Wear a medical ID bracelet or chain, and carry a card that describes your disease and details of your medication and dosage times.
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If you miss a dose before a meal, skip that dose. If it is almost time for your next dose, take only that dose with the next scheduled meal as directed. Do not take double or extra doses.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Low blood sugar (hypoglycemia)—tremors or shaking, anxiety, sweating, cold or clammy skin, confusion, dizziness, rapid heartbeat
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
-Back pain
-Diarrhea
-Headache
-Joint pain
-Nausea
-Runny or stuffy nose
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children and pets.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep container tightly closed. Throw away any unused medication after the expiration date.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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