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DANTROLENE (DAN troe leen) prevents and treats malignant hyperthermia, a severe reaction to some medications used for anesthesia. It works by relaxing your muscles. This reduces muscle stiffness and decreases body temperature. It belongs to a group of medications called muscle relaxants.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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This medication is injected into a vein. It is given by your care team in a hospital or clinic setting.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Do not take this medication with any of the following:
-Opioids for cough
This medication may also interact with the following:
-Alcohol
-Benzodiazepines, such as alprazolam, diazepam, or lorazepam
-Certain antihistamines
-Certain medications for blood pressure, heart disease, irregular heartbeat
-Certain medications for depression, such as amitriptyline or trazodone
-Certain medications for seizures, such as phenobarbital or primidone
-Estrogen and progestin hormones
-Medications that cause drowsiness before a procedure, such as propofol
-Medications that help you fall asleep
-Medications that relax muscles
-Opioids for pain
-Phenothiazines, such as chlorpromazine, prochlorperazine, thioridazine
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Your condition will be monitored carefully while you are receiving this medication.
This medication may affect your coordination, reaction time, or judgement. Do not drive or operate machinery until you know how this medication affects you. Sit up or stand slowly to reduce the risk of dizzy or fainting spells. Drinking alcohol with this medication can increase the risk of these side effects.
If you are taking another medication that also causes drowsiness, you may have more side effects. Give your care team a list of all medications you use. Your care team will tell you how much medication to take. Do not take more medication than directed. Call emergency services for help if you have problems breathing or unusual sleepiness.
This medication can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and sunscreen. Do not use sun lamps or tanning beds/booths.
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This does not apply.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Dry cough, shortness of breath or trouble breathing
-Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
-Diarrhea
-Dizziness
-Drowsiness
-Skin reactions on sun-exposed areas
-Unusual weakness or fatigue
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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This medication is given in a hospital or clinic. It will not be stored at home.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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