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GRANISETRON (gra NI se tron) prevents nausea and vomiting from chemotherapy. It works by blocking substances in your body that may cause nausea and vomiting. It belongs to a class of medications called antiemetics.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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This medication is for external use only. Follow the directions on the prescription label. Apply the patch to an area of the upper, outer arm that is clean and dry. Avoid injured, irritated, calloused, or scarred areas. Use a different site each time to prevent skin irritation. Do not cut or trim the patch. One patch can last for up to 7 days. Do not use your medication more often than directed. Do not stop using except on the advice of your care team.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Do not take this medication with any of the following:
-Apomorphine
-Cisapride
-Dronedarone
-Ketoconazole
-Pimozide
-Thioridazine
This medication may also interact with the following:
-Linezolid
-Methylene blue
-Opioids
-Other medications that cause heart rhythm changes
-Some medications for depression, anxiety, or other mental health conditions
Other medications may affect the way this medication works. Talk with your care team about all the medications you take. They may suggest changes to your treatment plan to lower the risk of side effects and to make sure your medications work as intended.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Your condition will be monitored after taking this medication.
The patch can make you more sensitive to the sun. Keep the area of your skin where the patch is applied out of the sun. Cover the patch with clothing if you cannot keep out of the sun. Continue to keep the area covered and out of the sun for 10 days after removing the patch. Do not use sun lamps or tanning beds/booths.
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It is important not to miss your dose. Notify your care team if you are not able to apply the patch 24 to 48 hours before starting chemotherapy.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Bowel blockage—stomach cramping, unable to have a bowel movement or pass gas, loss of appetite, vomiting
-Irritability, confusion, fast or irregular heartbeat, muscle stiffness, twitching muscles, sweating, high fever, seizure, chills, vomiting, diarrhea, which may be signs of serotonin syndrome
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
-Constipation
-Diarrhea
-Headache
-Stomach pain
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Keep this medication in the original package until you are ready to use it. Get rid of any unused medication after the expiration date. When you take off a used patch, fold it, so the sticky sides press together. This helps prevent others from contact with medication still in the patch.
To get rid of medications that are no longer needed or have expired:
-Take the medication to a take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medication, ask your pharmacist or care team how to get rid of it safely.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.