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COLLAGENASE (kohl LAH jen ace) treats skin ulcers and severe burns. It works by promoting healing and new skin growth.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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This medication is for external use only. Do not take by mouth. Wash the wound as directed by your care team. Do not scrub. If you are applying a topical antibiotic to the wound, apply the antibiotic before this medication. Do not touch the tip of the ointment tube with any surface, especially your fingers or the wound. Try to only get the ointment on the wound itself. If some gets on normal skin, wipe away with a sterile gauze pad. Do not use your medication more often than directed.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Do not take this medication with any of the following:
-Aluminum acetate, Burow's solution
-Povidone iodine
-Silver nitrate
-Silver sulfadiazine
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Visit your care team for regular checks on your progress. If your wound begins to look worse, smell bad, has colored discharge or more discharge, or increases in size, contact your care team. You may have an infection or need a change in your treatment.
If you develop a fever, chills, low blood pressure, dizziness, rapid heartbeat, or confusion, contact your care team immediately. You may have an infection of your blood.
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If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
-Mild skin irritation, redness, or dryness
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children and pets.
Store below 25 degrees C (77 degrees F). Throw away any unused medication after the expiration date.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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