TRODELVY

SACITUZUMAB GOVITECAN (SAK i TOOZ ue mab GOE vi TEE can) treats breast cancer. It works by blocking a protein that causes cancer cells to grow and multiply. This helps to slow or stop the spread of cancer cells.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

This medication is infused into a vein. It is given by your care team in a hospital or clinic setting.
This medication is not approved for use in children.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.

This medication may affect how other medications work, and other medications may affect the way this medication works. Talk with your care team about all of the medications you take. They may suggest changes to your treatment plan to lower the risk of side effects and to make sure your medications work as intended.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

This medication may make you feel generally unwell. This is not uncommon as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your care team tells you to stop.
You may need blood work while you are taking this medication.
Certain genetic factors may decrease the safety of this medication. Your care team may use genetic tests to determine treatment.
This medication can cause serious allergic reactions. To reduce your risk, your care team may give you other medications to take before receiving this one. Be sure to follow the directions from your care team.
Check with your care team if you have severe diarrhea, nausea, and vomiting, or if you sweat a lot. The loss of too much body fluid may make it dangerous for you to take this medication.
Talk to your care team if you wish to become pregnant or think you might be pregnant. This medication can cause serious birth defects if taken during pregnancy or if you get pregnant within 6 months after stopping treatment. A negative pregnancy test is required before starting this medication. A reliable form of contraception is recommended while taking this medication and for 6 months after stopping treatment. Talk to your care team about reliable forms of contraception.
Use a condom during sex and for 3 months after stopping treatment. Tell your care team right away if you think your partner might be pregnant. This medication can cause serious birth defects.
Do not breast-feed while taking this medication and for 1 month after stopping therapy.
This medication may cause infertility. Talk to your care team if you are concerned about your fertility.
This medication may increase your risk of getting an infection. Call your care team for advice if you get a fever, chills, sore throat, or other symptoms of a cold or flu. Do not treat yourself. Try to avoid being around people who are sick.
Avoid taking medications that contain aspirin, acetaminophen, ibuprofen, naproxen, or ketoprofen unless instructed by your care team. These medications may hide a fever.
This medication may increase blood sugar. The risk may be higher in patients who already have diabetes. Ask your care team what you can do to lower your risk of diabetes while taking this medication.

Keep appointments for follow-up doses. It is important not to miss your dose. Call your care team if you are unable to keep an appointment.

Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Infection—fever, chills, cough, or sore throat
-Infusion reactions—chest pain, shortness of breath or trouble breathing, feeling faint or lightheaded
-Low red blood cell level—unusual weakness or fatigue, dizziness, headache, trouble breathing
-Severe or prolonged diarrhea
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
-Constipation
-Diarrhea
-Fatigue
-Hair loss
-Loss of appetite
-Nausea
-Vomiting

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

This medication is given in a hospital or clinic. It will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.