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EPLONTERSEN (e PLON TER sen) treats nerve pain, tingling, or numbness in the hands or feet in people with transthyretin amyloidosis (ATTR). It works by reducing the buildup of a protein in your body. This decreases symptoms.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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This medication is injected under the skin. You will be taught how to prepare and give it. Take it as directed on the prescription label. Keep taking it unless your care team tells you to stop.
It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or care team to get one.
This medication comes with INSTRUCTIONS FOR USE. Ask your pharmacist for directions on how to use this medication. Read the information carefully. Talk to your pharmacist or care team if you have questions.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Interactions have not been studied.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.
Tell your care team right away if you have any change in your eyesight.
You should make sure you get enough vitamin A while you are taking this medication. Discuss the foods you eat and the vitamins you take with your care team.
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If you miss a dose, take it as soon as you can. Then continue your normal schedule. If it is almost time for your next dose, take only that dose. Do not take double or extra doses. Call your care team with questions.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Low vitamin A level—change in vision, dry eyes, dry skin, frequent infections
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
-Blurry vision
-Pain, redness, or irritation at injection site
-Vomiting
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children and pets.
Store in a refrigerator or at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Keep this medication in the original carton until you are ready to take it. Protect from light. Do not expose to extreme heat.
Refrigeration (preferred): Store in the refrigerator. Do not freeze. Get rid of any unused medication after the expiration date.
Room Temperature: This medication may be stored at room temperature for up to 6 weeks. If it is stored at room temperature, get rid of any unused medication after 6 weeks or after it expires, whichever is first.
To get rid of medications that are no longer needed or have expired:
-Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medication, ask your pharmacist or care team how to get rid of this medication safely.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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