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LENACAPAVIR (LEN a KAP a vir) is used for HIV PrEP (pre-exposure prophylaxis), which helps lower the risk of getting HIV through sex. It works by limiting the spread of HIV in the body. It does not prevent other sexually transmitted infections (STIs).
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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Take this medication by mouth with water. You can take it with or without food. If it upsets your stomach, take it with food. For your therapy to work as well as possible, take each dose exactly as prescribed on the prescription label. Do not skip doses.
Talk to your care team about the use of this medication in children. While it may be prescribed for children as young as 13 years for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Do not take this medication with any of the following:
-Barbiturates, such as butalbital, phenobarbital, pentobarbital
-Flibanserin
-Lomitapide
-Lonafarnib
-Lumacaftor; ivacaftor
-Rifampin
-Some medications for cancer, such as apalutamide, encorafenib, enzalutamide, mitotane
-Some medications for seizures, such as carbamazepine, phenytoin, primidone
-St. John's wort
This medication may also interact with the following:
-Digoxin
-Ergot alkaloids, such as dihydroergotamine, ergotamine, methylergonovine
-Naloxegol
-Some antivirals for HIV or hepatitis
-Some benzodiazepines, such as midazolam or triazolam
-Some medications for cholesterol, such as lovastatin or simvastatin
-Some medications for erectile dysfunction and pulmonary arterial hypertension, such as sildenafil, tadalafil, vardenafil
-Some medications for pain, such as buprenorphine, fentanyl, methadone, oxycodone, tramadol
-Some medications that prevent or treat blood clots, such as dabigatran, edoxaban, rivaroxaban
-Some steroid medications, such as cortisone, dexamethasone, hydrocortisone
This medication may affect how other medications work, and other medications may affect the way this medication works. Talk with your care team about all the medications you take. They may suggest changes to your treatment plan to lower the risk of side effects and to make sure your medications work as intended.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Visit your care team for regular health checks while on this medication.
You may need blood work done while you are taking this medication.
HIV is spread to others through sexual or blood contact. Talk to your care team about how to stop the spread of HIV.
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It is important not to miss your dose. If you miss your dose on Day 2, take it as soon as possible. Do not take Day 1 and Day 2 doses on the same day.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
-Diarrhea
-Dizziness
-Headache
-Nausea
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Keep this medication in the original container. Protect from moisture. Keep the container tightly closed. Do not throw out the packet in the container. It keeps the medication dry. Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or have expired:
-Take the medication to a take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, empty the medication out of the container. Mix it with cat litter, dirt, coffee grounds, or another unwanted substance. Seal the mixture in a bag or container. Put it in the trash.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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